Variotin
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus.
For research use only. We do not sell to patients.
- CAS No.: 19504-77-9
- Formula: C17H25NO3
- Molecular Weight:291.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MOLT-4 | IC50 |
>200 μM
Compound: 1
|
Inhibition of DNA polymerase delta isolated from human MOLT4 cells assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins
Inhibition of DNA polymerase delta isolated from human MOLT4 cells assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins
|
[PMID: 24411199] |
| MOLT-4 | IC50 |
>200 μM
Compound: 1
|
Inhibition of DNA polymerase epsilon isolated from human MOLT4 cells assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins
Inhibition of DNA polymerase epsilon isolated from human MOLT4 cells assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins
|
[PMID: 24411199] |
Chemical Information
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CAS No. 19504-77-9
-
Molecular Weight 291.39
-
Formula C17H25NO3
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SMILES
O=C1N(C(/C=C/C=C/C(C)=C/[C@H](O)CCCC)=O)CCC1
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Structure Classification
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Initial Source
Paecilomyces varioti Bainer var.
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)