N-Nitrosomorpholine-d8
Based on 1 Customer Validation
N-Nitrosomorpholine-d8 is deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen.
For research use only. We do not sell to patients.
- Purity: 99.74%
- CAS No.: 1219805-76-1
- Formula: C4D8N2O2
- Molecular Weight:124.17
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219805-76-1
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Unlabeled Cas 59-89-2
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Appearance Liquid
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Molecular Weight 124.17
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Formula C4D8N2O2
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Color Colorless to light yellow
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SMILES
O=NN1C([2H])([2H])C([2H])([2H])OC([2H])([2H])C1([2H])[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (805.35 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. K D Brunnemann, et al. N-Nitrosomorpholine and Other Volatile N-nitrosamines in Snuff Tobacco. Carcinogenesis. 1982;3(6):693-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.0535 mL | 40.2674 mL | 80.5348 mL | 201.3369 mL |
| 5 mM | 1.6107 mL | 8.0535 mL | 16.1070 mL | 40.2674 mL | |
| 10 mM | 0.8053 mL | 4.0267 mL | 8.0535 mL | 20.1337 mL | |
| 15 mM | 0.5369 mL | 2.6845 mL | 5.3690 mL | 13.4225 mL | |
| 20 mM | 0.4027 mL | 2.0134 mL | 4.0267 mL | 10.0668 mL | |
| 25 mM | 0.3221 mL | 1.6107 mL | 3.2214 mL | 8.0535 mL | |
| 30 mM | 0.2684 mL | 1.3422 mL | 2.6845 mL | 6.7112 mL | |
| 40 mM | 0.2013 mL | 1.0067 mL | 2.0134 mL | 5.0334 mL | |
| 50 mM | 0.1611 mL | 0.8053 mL | 1.6107 mL | 4.0267 mL | |
| 60 mM | 0.1342 mL | 0.6711 mL | 1.3422 mL | 3.3556 mL | |
| 80 mM | 0.1007 mL | 0.5033 mL | 1.0067 mL | 2.5167 mL | |
| 100 mM | 0.0805 mL | 0.4027 mL | 0.8053 mL | 2.0134 mL |
N-Nitrosomorpholine-d8 Related Classifications
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