Nav1.8-IN-16

Nav1.8-IN-16 (Compound (R)-40) is an orally active and selective hNaV 1.8 inhibitor (IC50: 5.9 nM). Nav1.8-IN-16 exerts analgesic effects by blocking NaV1.8 channels without significantly affecting other NaV subtypes or hERG channels. Nav1.8-IN-16 exhibits dose-dependent analgesic effects in postoperative pain and inflammatory pain models and can be used in pain-related research.

For research use only. We do not sell to patients.

  • Formula: C24H16ClF5N2O3
  • Molecular Weight:510.84
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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