ND-2158

ND-2158 is a competitive IRAK4 inhibitor, with the Ki of 1.3 nM. ND-2158 suppresses LPS-induced TNF production in human white blood cells, alleviated collagen-induced arthritis, and blocked gout formation in mouse models. ND-2158 has antitumor activity in vivo.

For research use only. We do not sell to patients.

  • CAS No.: 1388896-07-8
  • Formula: C22H30N4O4S
  • Molecular Weight:446.56
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All IRAK Isoforms

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