Nelumol A
Nelumol A is a farnesoid X receptor (FXR) agonist.
For research use only. We do not sell to patients.
- CAS No.: 77836-86-3
- Formula: C21H30O4
- Molecular Weight:346.46
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
3.4 x 10-5 M
Compound: 6
|
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
|
[PMID: 12088436] |
| A549 | IC50 |
76 μM
Compound: 36
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
| HL-60 | IC50 |
6.7 μM
Compound: 6
|
Cytotoxicity against human HL60 cells by SRB assay
Cytotoxicity against human HL60 cells by SRB assay
|
[PMID: 12088436] |
| HL-60 | IC50 |
6.7 x 10-6 M
Compound: 6
|
Cytotoxicity against human HL60 cells by SRB assay
Cytotoxicity against human HL60 cells by SRB assay
|
[PMID: 12088436] |
| KB | IC50 |
3 μM
Compound: 6
|
Cytotoxicity against human KB cells after 72 hrs
Cytotoxicity against human KB cells after 72 hrs
|
[PMID: 12088436] |
| KB | IC50 |
3 x 10-6 M
Compound: 6
|
Cytotoxicity against human KB cells after 72 hrs
Cytotoxicity against human KB cells after 72 hrs
|
[PMID: 12088436] |
| LoVo | IC50 |
38 μM
Compound: 36
|
Cytotoxicity against human LoVo cells after 72 hrs by MTT assay
Cytotoxicity against human LoVo cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
| PC-3 | IC50 |
40 μM
Compound: 36
|
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
| SK-MEL-28 | IC50 |
72 μM
Compound: 36
|
Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay
Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
| U-373MG ATCC | IC50 |
42 μM
Compound: 36
|
Cytotoxicity against human U373 cells after 72 hrs by MTT assay
Cytotoxicity against human U373 cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
Chemical Information
-
CAS No. 77836-86-3
-
Molecular Weight 346.46
-
Formula C21H30O4
-
SMILES
C/C(C)=C/CC/C(C)=C/COC1=C(C=C(/C=C/CO)C=C1OC)OC
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)