DB293
DB293 is a dicationic bis-amidine compound that potently recognizes mixed base pair sequences. DB293 binds to the minor groove of the ATGA sequence as an antiparallel stacked dimer through positive cooperativity. DB293 forms monomeric complexes with ATATAT and AAATTT, with no significant selectivity preference for these two sequences.
For research use only. We do not sell to patients.
- CAS No.: 216308-19-9
- Formula: C19H16N6O
- Molecular Weight:344.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
DB293 (20 μM) forms a cooperative 2:1 dimer with the ATGA sequence and 1:1 monomer complexes with ATATAT and AAATTT sequences, with the highest affinity observed for the ATGA dimer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 216308-19-9
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Molecular Weight 344.37
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Formula C19H16N6O
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SMILES
N=C(C1=CC=C(C2=CC=C(C3=NC4=CC=C(C(N)=N)C=C4N3)O2)C=C1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DB293 Related Classifications
HY-187606 Related Classifications
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