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Cat. No.: HY-153771

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Du011

Du011 is an E. coli polysaccharide capsule biogenesis inhibitor that targets MprA. Du011 can be used in research against E. coli infection.

For research use only. We do not sell to patients.

CAS No.: 890818-51-6
Formula: C₂₀H₁₅F₂NO₄S
Molecular Weight:403.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Du011 Chemical Structure

CAS No.: 890818-51-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Du011 is an E. coli polysaccharide capsule biogenesis inhibitor that targets MprA. Du011 can be used in research against E. coli infection^[1].

IC₅₀ & Target

MprA, Bacterial^[1].

Chemical Information

CAS No. 890818-51-6
Molecular Weight 403.40
Formula C₂₀H₁₅F₂NO₄S
SMILES

O=C(C1=C(NC(C2=C(F)C=CC=C2F)=O)C=C(C3=CC=C(OCC)C=C3)S1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Arshad M, et al. Optimization of a Noncanonical Anti-infective: Interrogation of the Target Binding Pocket for a Small-Molecule Inhibitor of Escherichia coli Polysaccharide Capsule Expression. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01208-20. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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