Talmapimod (Standard)
Talmapimod (Standard) is the analytical standard of Talmapimod (HY-10406). This product is intended for research and analytical applications. Talmapimod (SCIO-469) is an orally active and selective inhibitor of p38α MAPK with an IC50 of 9 nM. Talmapimod inhibits the secretion of inflammatory factors (such as TNFα, IL-1β, IL-6, and VEGF) by suppressing the p38α MAPK pathway, and it also inhibits angiogenesis and osteoclast activation. Talmapimod inhibits the growth of multiple myeloma cells and induces apoptosis. Talmapimod can be used to study various hematological malignancies (such as multiple myeloma, myelodysplastic syndrome).
For research use only. We do not sell to patients.
- Purity : 95%
- CAS No.: 309913-83-5
- Formula: C27H30ClFN4O3
- Molecular Weight:513.00
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-10406
Talmapimodp38α MAPK Inhibitor -
HY-10256
Adezmapimodp38 MAPK Inhibitor -
HY-10295
SB 202190p38 MAPK Inhibitor -
HY-10578
PD 169316p38 MAP Kinase Inhibitor -
HY-10401
VX-702p38α MAPK Inhibitor -
HY-10328
Neflamapimodp38α Inhibitor -
HY-14975
R1487 Hydrochloridep38α Inhibitor -
HY-11068
SB 239063p38 MAPK Inhibitor -
HY-10403
PH-797804p38α/β Inhibitor -
HY-10320
Doramapimodp38 MAPK Inhibitor -
HY-10456
TAK-715p38 MAPK Inhibitor -
HY-10404
Dilmapimodp38 MAPK Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 309913-83-5
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Molecular Weight 513.00
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Formula C27H30ClFN4O3
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SMILES
O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3[C@H](C)CN(CC4=CC=C(F)C=C4)[C@@H](C)C3)=O)C(Cl)=C2)=O
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Synonyms
SCIO-469 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Talmapimod (Standard) Related Classifications
HY-10406R Related Classifications
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