Vitamin D3-d6
Based on 1 Customer Validation
Vitamin D3-d6 (Cholecalciferol-d6 ) is the deuterium labeled Vitamin D3 (HY-15398) . Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
For research use only. We do not sell to patients.
- Purity: 98.47%
- CAS No.: 118584-54-6
- Formula: C27H38D6O
- Molecular Weight:390.67
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Storage:
-80°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 118584-54-6
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Unlabeled Cas 67-97-0
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Appearance Solid
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Molecular Weight 390.67
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Formula C27H38D6O
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Color White to light yellow
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C([2H])([2H])[2H])C([2H])([2H])[2H])([H])/C(CCC1)=C/C=C3C(CC[C@@H](C\3)O)=C
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Synonyms
Cholecalciferol-d6; Colecalciferol-d6
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Shipping
Shipping with dry ice.
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Storage
-80°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
DMSO : 66.67 mg/mL (170.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Nazik Al-Hashimi, et al. Cholecalciferol
[2]. Laura Bergadà, et al. Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma. Lab Invest. 2014 Jun;94(6):608-22 [Content Brief]
[3]. Hiroki Yoshioka, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12(4):e0176524. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5597 mL | 12.7985 mL | 25.5971 mL | 63.9926 mL |
| 5 mM | 0.5119 mL | 2.5597 mL | 5.1194 mL | 12.7985 mL | |
| 10 mM | 0.2560 mL | 1.2799 mL | 2.5597 mL | 6.3993 mL | |
| 15 mM | 0.1706 mL | 0.8532 mL | 1.7065 mL | 4.2662 mL | |
| 20 mM | 0.1280 mL | 0.6399 mL | 1.2799 mL | 3.1996 mL | |
| 25 mM | 0.1024 mL | 0.5119 mL | 1.0239 mL | 2.5597 mL | |
| 30 mM | 0.0853 mL | 0.4266 mL | 0.8532 mL | 2.1331 mL | |
| 40 mM | 0.0640 mL | 0.3200 mL | 0.6399 mL | 1.5998 mL | |
| 50 mM | 0.0512 mL | 0.2560 mL | 0.5119 mL | 1.2799 mL | |
| 60 mM | 0.0427 mL | 0.2133 mL | 0.4266 mL | 1.0665 mL | |
| 80 mM | 0.0320 mL | 0.1600 mL | 0.3200 mL | 0.7999 mL | |
| 100 mM | 0.0256 mL | 0.1280 mL | 0.2560 mL | 0.6399 mL |
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