Oleoylestrone
Oleoylestrone, an adipose tissue-derived hormonal signal, is a slimming agent that decreases food intake and maintains energy expenditure.
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- CAS No.: 180003-17-2
- 화학식: C36H54O3
- 분자량:534.81
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | EC50 |
~ 10 nM
Compound: 1-oleoyl (table 1)
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Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells
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[PMID: 15857137] |
In Vitro
Oleoylestrone is an adipose tissue-derived hormonal signal that elicits the decrease of body fat stores. This is accomplished by decreasing white adipose tissue mass through apoptosis and massive loss of lipid, accompanied by a decrease in food intake and the maintenance of energy expenditure[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 180003-17-2
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분자량 534.81
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화학식 C36H54O3
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SMILES
C[C@]12[C@]([H])([C@@]3(CCC4=C([C@]3(CC2)[H])C=CC(OC(CCCCCCC/C=C\CCCCCCCC)=O)=C4)[H])CCC1=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Large-size fat particle sorting
Large-size fat particle sorting is widely used to isolate cells up to 200 μm in diameter. Single-cell flow sorting will allow greater insight into adipocyte heterogeneity by identifying gene expression, protein composition, and metabolic signatures at the single-cell level.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Oleoylestrone Related Classifications
HY-125088 Related Classifications
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