OX2R agonist-4
OX2R agonist-4 is an orexin receptor type 2 (OX2R) agonist with an EC50 value of 0.061 nM against human OX2R. OX2R agonist-4 can be used in studies related to narcolepsy.
For research use only. We do not sell to patients.
- CAS No.: 3132407-42-9
- Formula: C23H24F2N2O4S
- Molecular Weight:462.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Orexin Receptor (OX Receptor) Isoforms
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Biological Activity
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human OX2R 0.061 nM (EC50) |
OX2R agonist-4 (Compound 86) is a human OX2R agonist. OX2R is a central Gq-coupled GPCR that equally recognizes orexin A/B, regulates arousal and sleep-wake homeostasis, and its dysfunction can trigger narcolepsy[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3132407-42-9
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Molecular Weight 462.51
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Formula C23H24F2N2O4S
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SMILES
CC1=CN=C(O1)[C@]2(CC3=CC=C(F)C(C4=CC=CC(O)=C4)=C3F)C[C@@H](NS(=O)(C)=O)CC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)