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Cat. No.: HY-176490

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pan-KRAS ligand 3

Pan-KRAS ligand 3 is a pan-KRAS inhibitor. Pan-KRAS ligand 3 can be used for synthesis of PROTAC pan-KRAS degrader-1 (HY-176489).

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Formule: C₂₅H₂₃ClF₂N₄O₂
Masse moléculaire:484.93

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

pan-KRAS ligand 3 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Pan-KRAS ligand 3 is a pan-KRAS inhibitor. Pan-KRAS ligand 3 can be used for synthesis of PROTAC pan-KRAS degrader-1 (HY-176489)^[1].

IC₅₀ & Target

pan-KRAS

Voir tous les produits spécifiques à Isoform Ras :

Chemical Information

Masse moléculaire 484.93
Formule C₂₅H₂₃ClF₂N₄O₂
SMILES

FC(C=C1)=C(CC)C(C1=CC(O)=C2)=C2C3=NC=C4C(N=C(Cl)N=C4N5CCC[C@@](C)(O)C5)=C3F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xu Renqi, et al. Pan-kras protein targeted degrader compound and use thereof. Patent. WO2025039676. 2025-02-27.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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pan-KRAS ligand 3

Voir tous les produits spécifiques à Isoform Ras

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

pan-KRAS ligand 3 Related Classifications

HY-176490 Related Classifications

Bioz

Keywords

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