PBZ1038
Based on 1 Customer Validation
PBZ1038 is a highly effective inhibitor of Gram-negative chaperone proteins, achieving its antibacterial effect by inhibiting GroES/GroEL.
For research use only. We do not sell to patients.
- Purity: 98.57%
- CAS No.: 2043687-46-1
- Formula: C25H19N3O7S2
- Molecular Weight:537.56
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
38 μM
Compound: 2h-p
|
Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by alamar blue assay
Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by alamar blue assay
|
[PMID: 27720295] |
Chemical Information
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CAS No. 2043687-46-1
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Appearance Solid
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Molecular Weight 537.56
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Formula C25H19N3O7S2
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Color White to off-white
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SMILES
O=S(NC1=CC=C(C2=NC3=CC(NS(=O)(C4=CC=C(C=C4)O)=O)=CC=C3O2)C=C1)(C5=CC=C(C=C5)O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (93.01 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8603 mL | 9.3013 mL | 18.6026 mL | 46.5064 mL |
| 5 mM | 0.3721 mL | 1.8603 mL | 3.7205 mL | 9.3013 mL | |
| 10 mM | 0.1860 mL | 0.9301 mL | 1.8603 mL | 4.6506 mL | |
| 15 mM | 0.1240 mL | 0.6201 mL | 1.2402 mL | 3.1004 mL | |
| 20 mM | 0.0930 mL | 0.4651 mL | 0.9301 mL | 2.3253 mL | |
| 25 mM | 0.0744 mL | 0.3721 mL | 0.7441 mL | 1.8603 mL | |
| 30 mM | 0.0620 mL | 0.3100 mL | 0.6201 mL | 1.5502 mL | |
| 40 mM | 0.0465 mL | 0.2325 mL | 0.4651 mL | 1.1627 mL | |
| 50 mM | 0.0372 mL | 0.1860 mL | 0.3721 mL | 0.9301 mL | |
| 60 mM | 0.0310 mL | 0.1550 mL | 0.3100 mL | 0.7751 mL | |
| 80 mM | 0.0233 mL | 0.1163 mL | 0.2325 mL | 0.5813 mL |
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