PCSK9-IN-36
PCSK9-IN-36 is a PCSK9 inhibitor and a flavonoid glycoside derivative. PCSK9-IN-36 binds stably within the surface groove of PCSK9 through hydrophobic interactions involving its flavonoid scaffold and an electrostatic hydrogen-bonding network formed by its polar glycosidic group, thereby competitively blocking the interaction between PCSK9 and the low-density lipoprotein receptor (LDLR). PCSK9-IN-36 can be used for research on hypercholesterolemia.
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- CAS No.: 94159-34-9
- Formule: C21H20O10
- Masse moléculaire:432.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Chemical Information
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CAS No. 94159-34-9
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Masse moléculaire 432.38
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Formule C21H20O10
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SMILES
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC(O)=C13
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PCSK9-IN-36 Related Classifications
HY-187677 Related Classifications
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