PDE5-IN-9
Based on 1 Customer Validation
PDE5-IN-9 (Compound 59) is a PDE5 inhibitor (IC50: 11.2 μM). PDE5-IN-9 shows interaction with Gln 817, Tyr 612, and Ala 767 amino acid residues. PDE5-IN-9 can be used for research of cardiovascular disease.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 157862-84-5
- Formula: C18H14N4S
- Molecular Weight:318.40
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
|
PDE5 |
Chemical Information
-
CAS No. 157862-84-5
-
Appearance Solid
-
Molecular Weight 318.40
-
Formula C18H14N4S
-
Color White to off-white
-
SMILES
C1(C2=CC=CN=C2)=NC(NCC3=CC=CS3)=C4C=CC=CC4=N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (314.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1407 mL | 15.7035 mL | 31.4070 mL | 78.5176 mL |
| 5 mM | 0.6281 mL | 3.1407 mL | 6.2814 mL | 15.7035 mL | |
| 10 mM | 0.3141 mL | 1.5704 mL | 3.1407 mL | 7.8518 mL | |
| 15 mM | 0.2094 mL | 1.0469 mL | 2.0938 mL | 5.2345 mL | |
| 20 mM | 0.1570 mL | 0.7852 mL | 1.5704 mL | 3.9259 mL | |
| 25 mM | 0.1256 mL | 0.6281 mL | 1.2563 mL | 3.1407 mL | |
| 30 mM | 0.1047 mL | 0.5235 mL | 1.0469 mL | 2.6173 mL | |
| 40 mM | 0.0785 mL | 0.3926 mL | 0.7852 mL | 1.9629 mL | |
| 50 mM | 0.0628 mL | 0.3141 mL | 0.6281 mL | 1.5704 mL | |
| 60 mM | 0.0523 mL | 0.2617 mL | 0.5235 mL | 1.3086 mL | |
| 80 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9815 mL | |
| 100 mM | 0.0314 mL | 0.1570 mL | 0.3141 mL | 0.7852 mL |