2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. PG106

PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

PG106 Chemical Structure

PG106 Chemical Structure

CAS No. : 944111-22-2

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PG106 Related Antibodies

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Description

PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor[1].

IC50 & Target

IC50: 210 nM (hMC3 receptor)
EC50: 9900 nM (hMC4 receptor)[1]
Molecular Weight

1008.18

Formula

C51H69N13O9
CAS No.
Sequence Shortening

Ac-{Nle}-D-{Bal}-{D-Nal}-RWK-NH2 (Lactam bridge:Asp2-Lys7)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PG106 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PG106944111-22-2PG 106PG-106Melanocortin ReceptorMC ReceptormelanocortinhMC3hMC4hMC5lactam derivativeInhibitorinhibitorinhibit

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