2. Metabolic Enzyme/Protease
  3. Aldehyde Oxidase (AO)
  4. Phenanthridine

Phenanthridine is an aldehyde oxidase 1 (AOX1) substrate, with oxidation by hAOX1 yielding phenanthridone when molecular oxygen, ferricyanide, or dichlorophenolindophenol serves as electron acceptor.

For research use only. We do not sell to patients.

Phenanthridine

Phenanthridine Chemical Structure

CAS No. : 229-87-8

Size Price Stock Quantity
50 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
100 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
250 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
500 mg Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
1 g Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks
5 g   Get quote  
10 g   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 Customer Validation

Phenanthridine Related Antibodies

Top Publications Citing Use of Products

View All Aldehyde Oxidase (AO) Isoform Specific Products:

View All Isoforms
AOX1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Phenanthridine is an aldehyde oxidase 1 (AOX1) substrate, with oxidation by hAOX1 yielding phenanthridone when molecular oxygen, ferricyanide, or dichlorophenolindophenol serves as electron acceptor[1].

IC50 & Target[1]

AOX1

 

Cellular Effect
Cell Line Type Value Description References
A549 IC50
50 μM
Compound: 5b
Cytotoxicity against human A549 cells incubated for 24 to 48 hrs by MTT assay
Cytotoxicity against human A549 cells incubated for 24 to 48 hrs by MTT assay
[PMID: 40147342]
In Vitro

Phenanthridine (40 μM) is used as substrate to show that in vitro chemical sulfuration increases the specific activity of hAOX1-WT, co-hAOX1, and hAOX1-S1271L by ~10-fold, with hAOX1-WT reaching 1516.7 mU/mg, co-hAOX1 reaching 1459.1 mU/mg, and hAOX1-S1271L reaching 1132.1 mU/mg after sulfuration[1].
Phenanthridine is used as substrate to show that codon-optimized hAOX1-WT has a pH optimum of ~8.0, while hAOX1-S1271L has a slightly shifted pH optimum of ~8.3[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Phenanthridine Related Antibodies
Molecular Weight

179.22

Formula

C13H9N
CAS No.
Appearance

Solid

SMILES

N1=CC2=CC=CC=C2C3=CC=CC=C13
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Phenanthridine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenanthridine229-87-8Aldehyde Oxidase (AO)Aldehyde OxidaseAOdichlorophenolindophenolhAOX1molecular oxygenco-hAOX1human aldehyde oxidase 1phenanthridonehAOX1-WThAOX1-S1271LferricyanideInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Phenanthridine
Cat. No.:
HY-W142745
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB) Italian - IT (252 KB) Korean - KR (252 KB) Portuguese - PT (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.