Phyltetralin
Phyltetralin (Compound 10) is a natural product than can be isolated from the hexane-ethyl acetate extract of Phyllanthus amarus leaves. Phyltetralin possesses immunosuppressive effects on different lineages of innate immune system.
For research use only. We do not sell to patients.
- CAS No.: 123048-17-9
- Formula: C24H32O6
- Molecular Weight:416.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Phyltetralin shows inhibition on Polymorphonuclear neutrophil (PMN) chemotaxis with an IC50 of 4.01 µM[2].
Phyltetralin shows strong inhibition against reactive oxygen species (ROS) production from PMA-stimulated neutrophil with an IC50 of 0.73 µM[2].
Phyltetralin shows weak inhibition on CD18 expression and moderate inhibition on engulfment activity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 123048-17-9
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Molecular Weight 416.51
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Formula C24H32O6
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SMILES
COC[C@@H]1[C@@H](COC)[C@H](C2=CC=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)