PLK1-IN-14
PLK1-IN-14 (Compound Hit-4) is a selective PLK1 inhibitor. It has an IC50 of 22.61 pM against PLK1 and an IC50 of 0.09 nM for inhibiting the proliferation of DU - 145 prostate cancer cells. PLK1-IN-14 can be used in the research of prostate cancer.
For research use only. We do not sell to patients.
- Formula: C41H55F5N8O3
- Molecular Weight:802.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PLK1 22.61 pM (IC50) |
Chemical Information
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Molecular Weight 802.92
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Formula C41H55F5N8O3
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SMILES
COC1=CC(C(NC2CCC(N3CCN(C[C@H]4CCC5(CCCC5)C4)CC3)CC2)=O)=C(F)C=C1NC6=NC=C(N(C)C(C(F)(F)CN7[C@H]8CCCC8(F)F)=O)C7=N6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)