PLK1-IN-15
PLK1-IN-15 (Compound 7n) is a PLK1 inhibitor (IC50: 38.5 nM). PLK1-IN-15 exhibits antiproliferative activity against HepG2, Huh7, H1299 and A549 cells (IC50: 2.03, 2.08, 4.79 and 17.11 μM, respectively). PLK1-IN-15 induces cell cycle arrest at the G2/M phase and apoptosis, and has anticancer activity.
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- CAS. Nr.: 3068529-37-0
- Formel: C25H29N7O4S
- Molecular Weight:523.61
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
PLK1 38.5 nM (IC50) |
Chemical Information
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CAS. Nr. 3068529-37-0
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Molecular Weight 523.61
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Formel C25H29N7O4S
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SMILES
O=C(OC)C1=C(SC2=C1CCCC2)NC3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=NC=C3[N+]([O-])=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PLK1-IN-15 Related Classifications
HY-172880 Related Classifications
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