Propaquizafop
Based on 1 Customer Validation
Propaquizafop is a phenoxyisopropionic acid herbicide and an acetyl-coA carboxylase inhibitor.
For research use only. We do not sell to patients.
- Purity: 98.33%
- CAS No.: 111479-05-1
- Formula: C22H22ClN3O5
- Molecular Weight:443.88
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Metabolism/Protease Compound Library
HY-L012
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Anti-Cancer Metabolism Compound Library
HY-L083
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Anti-Obesity Compound Library
HY-L087
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Lipid Metabolism Compound Library
HY-L091
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Metabolic Enzyme Compound Library
HY-L146
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MCE Bioactive Compound Library
HY-L001V
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Pesticide Compound Library
HY-L183
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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CAS No. 111479-05-1
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Appearance Solid
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Molecular Weight 443.88
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Formula C22H22ClN3O5
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Color White to off-white
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SMILES
C[C@H](C(OCCO/N=C(C)\C)=O)OC1=CC=C(C=C1)OC2=NC3=CC=C(C=C3N=C2)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (225.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Bouis, et al. Effect of Propaquizafop and Its Free-Acid Derivative on Lauric Acid Hydroxylation and Peroxisomal Beta-Oxidation in Primary Cultured Rat, Mouse, Guinea Pig and Marmoset Hepatocytes. Toxicol In Vitro. 1993 Jul;7(4):427-31. [Content Brief]
[2]. Laura R Davies, et al. Detection and Characterization of Resistance to Acetolactate Synthase Inhibiting Herbicides in Anisantha and Bromus Species in the United Kingdom. Pest Manag Sci. 2020 Jul;76(7):2473-2482. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2529 mL | 11.2643 mL | 22.5286 mL | 56.3215 mL |
| 5 mM | 0.4506 mL | 2.2529 mL | 4.5057 mL | 11.2643 mL | |
| 10 mM | 0.2253 mL | 1.1264 mL | 2.2529 mL | 5.6322 mL | |
| 15 mM | 0.1502 mL | 0.7510 mL | 1.5019 mL | 3.7548 mL | |
| 20 mM | 0.1126 mL | 0.5632 mL | 1.1264 mL | 2.8161 mL | |
| 25 mM | 0.0901 mL | 0.4506 mL | 0.9011 mL | 2.2529 mL | |
| 30 mM | 0.0751 mL | 0.3755 mL | 0.7510 mL | 1.8774 mL | |
| 40 mM | 0.0563 mL | 0.2816 mL | 0.5632 mL | 1.4080 mL | |
| 50 mM | 0.0451 mL | 0.2253 mL | 0.4506 mL | 1.1264 mL | |
| 60 mM | 0.0375 mL | 0.1877 mL | 0.3755 mL | 0.9387 mL | |
| 80 mM | 0.0282 mL | 0.1408 mL | 0.2816 mL | 0.7040 mL | |
| 100 mM | 0.0225 mL | 0.1126 mL | 0.2253 mL | 0.5632 mL |
Propaquizafop Related Classifications
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