2. Recombinant Proteins
  3. Ubiquitin Related Proteins
  4. Ubiquitin Enzymes
  5. E1 Enzymes
  6. SAE1

SAE1

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Cat. No. Product Name / Synonyms Species Source
  • HY-P71643
    SAE1 Protein, Human (GST)

    Activator of SUMO1; AOS1; HSPC140; Sae1; SAE1_HUMAN; Sentrin/SUMO activating protein AOS1; UBL E1A; UBLE1A

    		Human E. coli
    SAE1 protein, forming a heterodimer, acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and potentially SUMO4. It critically mediates ATP-dependent activation of SUMO proteins, enabling the formation of a thioester bond with UBA2/SAE2's active site cysteine. This process is essential for protein modification through sumoylation. SAE1 Protein, Human (GST) is the recombinant human-derived SAE1 protein, expressed by E. coli , with N-GST labeled tag. The total length of SAE1 Protein, Human (GST) is 346 a.a., with molecular weight of ~65.4 kDa.
Cat. No. Product Name Effect Purity