Ubiquitin-Conjugating Enzyme E2 E1
Ubiquitin-conjugating enzyme E2 E1 (UBCH6) heads the three-member UBE2E family and, like its relatives, combines the UBC core with short flanking extensions. E2 E family enzymes are noted for efficient polyubiquitin chain initiation and for pairing with large multidomain ligases, including the APC/C and NEDD4-family HECT enzymes. UBE2E1 is broadly expressed with prominent neuronal levels and participates in cell cycle control and degradation of short-lived regulators. Because the three UBE2E paralogs overlap substantially, much of E2 E1 biology has been dissected together with E2 E2 and E2 E3. Recombinant E2 E1 is used in vitro with APC/C and HECT ligases for chain-building assays.
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Ubiquitin-Conjugating Enzyme E2 E1 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
