PSB-0739 (Standard)
PSB-0739 (Standard) is the analytical standard of PSB-0739 (HY-108660). This product is intended for research and analytical applications. PSB-0739 is a high-affinity potent, competitive, nonselective platelet P2Y12 receptor antagonist with a Ki values of 24.9 nM. The P2Y12 receptor plays a crucial role in platelet aggregation. Antithrombotic effect.
For research use only. We do not sell to patients.
- CAS No.: 1052087-90-7
- Formula: C26H17N3Na2O8S2
- Molecular Weight:609.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1052087-90-7
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Molecular Weight 609.54
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Formula C26H17N3Na2O8S2
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SMILES
O=S(C(C(N)=C1C2=O)=CC(NC3=CC=C(NC4=CC=CC=C4)C(S(=O)(O[Na])=O)=C3)=C1C(C5=C2C=CC=C5)=O)(O[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Younis Baqi, et al. High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. J Med Chem. 2009 Jun 25;52(12):3784-93. [Content Brief]
[2]. Kristina Hoffmann, et al. Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor. J Pharmacol Exp Ther. 2009 Nov;331(2):648-55. [Content Brief]
[3]. J J Micklewright,et al. P2Y 12 receptor modulation of ADP-evoked intracellular Ca2+ signalling in THP-1 human monocytic cells. Br J Pharmacol.2018 Jun;175(12):2483-2491. [Content Brief]
[4]. Gergely Horváth, et al. Central P2Y12 receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents. Neurobiol Dis. 2014 Oct;70(100):162-78. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PSB-0739 (Standard) Related Classifications
HY-108660R Related Classifications
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