Pteroylhexaglutamate
Pteroylhexaglutamate (PteGlu6) inhibits the T2-phage-induced synthetase by 50% at 0.6 μM in the absence of Mg2+. Pteroylhexaglutamate is a substrate for pteroylpolyglutamate hydrolase, and can be used to monitor the activity of pteroylpolyglutamate hydrolase.
For research use only. We do not sell to patients.
- CAS No.: 35409-55-3
- Formula: C44H54N12O21
- Molecular Weight:1086.97
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Chemical Information
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CAS No. 35409-55-3
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Appearance Solid
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Molecular Weight 1086.97
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Formula C44H54N12O21
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Color Light yellow to yellow
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SMILES
O=C1C2=NC(CNC(C=C3)=CC=C3C(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)=O)=O)=CNC2=NC(N)=N1
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Synonyms
PteGlu6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Maley GF, et al. Differential inhibition of host and viral thymidylate synthetases by folylpolyglutamates. J Biol Chem. 1979 Aug 25;254(16):7485-7. [Content Brief]
[2]. Seyoum E, et al. Properties of food folates determined by stability and susceptibility to intestinal pteroylpolyglutamate hydrolase action. J Nutr. 1998 Nov;128(11):1956-60. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)