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Cat. No.: HY-N19911

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Pubetallin

Pubetallin is a germacrane-type sesquiterpenoid (germacranolide) can be found in the aerial parts of Sigesbeckia orientalis. Pubetallin induces cytotoxicity in breast cancer cells. Pubetallin can be used for the research of breast cancer.

For research use only. We do not sell to patients.

CAS No.: 75207-37-3
Formula: C₂₀H₂₄O₇
Molecular Weight:376.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pubetallin Chemical Structure

CAS No.: 75207-37-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Pubetallin (24 h) shows moderate cytotoxicity against human MDA-MB-231 breast cancer cells with an IC₅₀ of 19.73 μM^[1].
Pubetallin (24 h) exhibits no significant cytotoxicity against human A549 lung cancer cells, with an IC₅₀ > 20 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 75207-37-3
Molecular Weight 376.40
Formula C₂₀H₂₄O₇
SMILES

C=C(C)C(O[C@@H]1[C@@H](OC)/C(C=O)=C\CC/C(CO)=C/[C@@]([C@]1([H])C2=C)([H])OC2=O)=O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Liu N, et al. Germacrane-type sesquiterpenoids with cytotoxic activity from Sigesbeckia orientalis. Bioorganic chemistry. 2019 Nov;92:103196. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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