KR025, a new cytotoxic compound from Myxococcus fulvus

  • J Nat Prod. 1999 Mar;62(3):495-6. doi: 10.1021/np9804233.
J W Ahn  1 ,  S H Woo ,  C O Lee ,  K Y Cho ,  B S Kim
Affiliations
  • 1. Korea Research Institute of Chemical Technology, P.O. Box 107, Taejon 305-600, Korea. [email protected]
PMID: 10096868 DOI: 10.1021/np9804233
Abstract

A new bithiazole, KR-025 (1), was isolated from Myxococcus fulvus. Its structure was elucidated by spectroscopic analysis. In addition to 1, the strain produced relatively large quantities of a second, closely related Antibiotic, myxothiazol. These compounds demonstrated potent cytotoxicity against human tumor cells.