Luisols A and B, new aromatic tetraols produced by an estuarine marine bacterium of the genus Streptomyces (Actinomycetales)

  • J Nat Prod. 1999 Apr;62(4):608-10. doi: 10.1021/np980415m.
X C Cheng  1 ,  P R Jensen ,  W Fenical
Affiliations
  • 1. Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California-San Diego, La Jolla, California 92093-0236, USA.
PMID: 10217720 DOI: 10.1021/np980415m
Abstract

Luisols A (1) and B (2), two new aromatic tetraols, have been isolated from the cultivation broth of an estuarine marine actinomycete of the genus Streptomyces (strain #CNH-370). The structures of luisols A and B were assigned by combined spectroscopic methods, including extensive 2D NMR experiments. Luisol A appears related to the anthraquinone Antibiotics of the granaticin class, while the structure of luisol B contains the rare epoxynaphtho[2,3c]furan, a structural feature found in only one natural product, the Fungal metabolite anthrinone.

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