Anti-emetic principles of Pogostemon cablin (Blanco) Benth

  • Phytomedicine. 1999 May;6(2):89-93. doi: 10.1016/S0944-7113(99)80041-5.
Y Yang  1 ,  K Kinoshita ,  K Koyama ,  K Takahashi ,  T Tai ,  Y Nunoura ,  K Watanabe
Affiliations
  • 1. Department of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University, Tokyo, Japan.
PMID: 10374246 DOI: 10.1016/S0944-7113(99)80041-5
Abstract

Bioassay-guided fractionation of anti-emetic extracts and constituents of 8 traditional Chinese herbal drugs was performed. Twenty extracts described in Table 1 showed anti-emetic activity on copper sulfate induced-emesis in young chicks. From the n-hexane extract of Pogostemon cablin, patchouli alcohol (1), pogostol (2), stigmast-4-en-3-one (3), retusin (4), and pachypodol (5) were tested and exhibited anti-emetic effects.

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