Novel bioactive sulfated alkene and alkanes from the mediterranean ascidian Halocynthia papillosa

  • J Nat Prod. 2000 Nov;63(11):1590-2. doi: 10.1021/np000281o.
A Aiello  1 ,  S Carbonelli ,  G Esposito ,  E Fattorusso ,  T Iuvone ,  M Menna
Affiliations
  • 1. Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, via D. Montesano 49, I-80131, Napoli, Italy.
PMID: 11087619 DOI: 10.1021/np000281o
Abstract

Three sulfated alkene and alkanes-(R)-2,6-dimethylheptyl sulfate (1), 6-methylheptyl sulfate (2a), and (E)-5-octenyl sulfate (3a)-with cytotoxic activity in vitro, have been isolated from the Mediterranean ascidian Halocynthia papillosa. The structures of the new compounds 2a and 3a have been elucidated by spectroscopic analysis.