Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity

  • Bioorg Med Chem Lett. 2001 Sep 17;11(18):2507-10. doi: 10.1016/s0960-894x(01)00471-1.
A Brancale  1 ,  C McGuigan ,  B Algain ,  P Savy ,  R Benhida ,  J L Fourrey ,  G Andrei ,  R Snoeck ,  E De Clercq ,  J Balzarini
Affiliations
  • 1. Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, CF10 3XF, Cardiff, UK.
PMID: 11549457 DOI: 10.1016/s0960-894x(01)00471-1
Abstract

Thieno analogues of the potent and selective furo-pyrimidine anti-VZV nucleoside family are herein reported. The compounds retain full Antiviral potency in comparison to the furo parent.