New multiflorane-type triterpenoid acids from Sandoricum indicum

  • J Nat Prod. 2001 Sep;64(9):1243-5. doi: 10.1021/np010196w.
T Tanaka  1 ,  T Koyano ,  T Kowithayakorn ,  H Fujimoto ,  E Okuyama ,  M Hayashi ,  K Komiyama ,  M Ishibashi
Affiliations
  • 1. Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
PMID: 11575968 DOI: 10.1021/np010196w
Abstract

Three new 12beta-hydroxymultiflorane triterpenoid acids, sandorinic acids A-C (1-3), were isolated from the stem bark of Sandoricum indicum together with five known Triterpenes (4-8). The structures of 1-3 were elucidated by spectral data interpretation. Compounds 1-8 were evaluated for their inhibiting activity against several tumor cell lines and for their effects on lymphocyte proliferation.