Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys
- J Nat Prod. 1992 Dec;55(12):1776-8. doi: 10.1021/np50090a011.
Affiliations
- 1. Kyoto Pharmaceutical University, Japan.
PMID: 1294698
DOI: 10.1021/np50090a011
Abstract
Afromosin [1] and soyasaponin I [2] isolated from Wistaria brachybotrys exhibited remarkable inhibitory effects on mouse skin tumor promotion, and afromosin also exhibited a significant inhibitory effect on pulmonary tumor promotion. The combined effects of these compounds on the two-stage skin carcinogenesis were also examined, and it was concluded that the combination of 1 with 2 enhanced the inhibitory effect.