Folipastatin, a new depsidone compound from Aspergillus unguis as an inhibitor of phospholipase A2. Taxonomy, fermentation, isolation, structure determination and biological properties

  • J Antibiot (Tokyo). 1992 Aug;45(8):1195-201. doi: 10.7164/antibiotics.45.1195.
K Hamano  1 ,  M Kinoshita-Okami ,  A Hemmi ,  A Sato ,  M Hisamoto ,  K Matsuda ,  K Yoda ,  H Haruyama ,  T Hosoya ,  K Tanzawa
Affiliations
  • 1. Fermentation Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.
PMID: 1399838 DOI: 10.7164/antibiotics.45.1195
Abstract

A new inhibitor of Phospholipase A2 was isolated from the fermentation broth of Aspergillus unguis. The structure, with a depsidone carbon skeleton, was assigned by spectroscopic experiments.

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