Triterpenoid saponins from leaves of Hedera pastuchowii

  • Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1411-5. doi: 10.1248/cpb.52.1411.
Vakhtang Mshvildadze  1 ,  Riad Elias ,  Robert Faure ,  David Rondeau ,  Laurent Debrauwer ,  Genri Dekanosidze ,  Ether Kemertelidze ,  Guy Balansard
Affiliations
  • 1. Institute of Pharmacochemistry, Academy of Sciences of Georgia, Tbilisi, Georgia.
PMID: 15577235 DOI: 10.1248/cpb.52.1411
Abstract

Five new triterpenoid saponins, pastuchoside A (1), B (3), C (5), D (7) and E (9), were isolated from the leaves of Hedera pastuchowii. They have oleanolic acid or hederagenin as aglycone. The structures were established by NMR spectroscopy including gs (gradient selected)-COSY, gs-HSQC, gs-HSQC-TOCSY and gs-HMBC experiments, and mass spectrometry (ESI-HR-MS). Heptaoside saponins, compounds 1 and 3, are described for the first time in the genus Hedera.

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