Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines

  • J Nat Prod. 2005 Mar;68(3):361-4. doi: 10.1021/np040175c.
Orawan Monthakantirat  1 ,  Wanchai De-Eknamkul ,  Kaoru Umehara ,  Yohko Yoshinaga ,  Toshio Miyase ,  Tsutomu Warashina ,  Hiroshi Noguchi
Affiliations
  • 1. Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
PMID: 15787436 DOI: 10.1021/np040175c
Abstract

From the rhizomes of Belamcanda chinensis, three new compounds, belalloside A (1), belalloside B (2), and belamphenone (3), along with 13 known compounds, resveratrol (4), iriflophenone (5), irisflorentin (6), tectorigenin (7), irilin D (8), tectoridin (9), iristectorin A (10), iristectorin B (11), hispiduloside, androsin, irigenin, iridin, and jaceoside, have been isolated and characterized. Isolates were evaluated for their cell proliferation stimulatory activity against the MCF-7 and T-47D human breast Cancer cell lines. Along with 4, 5, 7, and 9, 3 was shown to stimulate not only MCF-7 but also T-47D human breast Cancer cell proliferation.

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