Antimicrobial activity of isopteropodine

  • Z Naturforsch C J Biosci. 2005 May-Jun;60(5-6):385-8. doi: 10.1515/znc-2005-5-603.
Rubén García  1 ,  Cesia Cayunao ,  Ronny Bocic ,  Nadine Backhouse ,  Carle Delporte ,  Mercedes Zaldivar ,  Silvia Erazo
Affiliations
  • 1. Department of Pharmacological and Toxicological Chemistry, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile. [email protected]
PMID: 16042336 DOI: 10.1515/znc-2005-5-603
Abstract

Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited Antibacterial activity against Gram positive bacteria.

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