Sporminarins A and B: antifungal metabolites from a fungicolous isolate of Sporormiella minimoides

  • J Antibiot (Tokyo). 2006 Aug;59(8):500-6. doi: 10.1038/ja.2006.70.
Sanjay V Mudur  1 James B Gloer Donald T Wicklow
Affiliations
  • 1. Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
Abstract

Cultures of a fungicolous isolate of Sporormiella minimoides afforded two new polyketide metabolites which we have named sporminarins A (1) and B (2). The planar structures of 1 and 2 were elucidated by analysis of NMR and MS data, and by chemical methods. 1 exhibited significant Antifungal activity against Aspergillus flavus.

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