Galactonic Acid in galactosemia: identification in the urine

  • Science. 1972 May 12;176(4035):683-4. doi: 10.1126/science.176.4035.683.
W R Bergren ,  W G Ng ,  G N Donnell ,  S P Markey
PMID: 17778172 DOI: 10.1126/science.176.4035.683
Abstract

Galactose is converted to galactonic acid in vivo in man. Galactonate was isolated from the urine of galactosemia patients who had been given galactose orally. The identity of the galactonate was established by gas-liquid chromatography and by the preparation of derivatives.

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