3-Alkylpyridinium alkaloids from the Pacific sponge Haliclona sp

  • J Nat Prod. 2009 Feb 27;72(2):301-3. doi: 10.1021/np800610p.
Agostino Casapullo  1 ,  Oscar Cobar Pinto ,  Stefania Marzocco ,  Giuseppina Autore ,  Raffaele Riccio
Affiliations
  • 1. Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte don Melillo, 84084 Fisciano, Italy. [email protected]
PMID: 19133758 DOI: 10.1021/np800610p
Abstract

The analysis of the polar extracts of the Pacific Sponge Haliclona sp. yielded new dimeric (1), trimeric (2), and polymeric 3-alkylpyridinium Alkaloids. Their isolation and structural elucidation, based on NMR and MS data, are discussed in detail, along with their cytotoxic activity.