Two new C(13) nor-isoprenoids from the leaves of Casearia sylvestris

  • Chem Pharm Bull (Tokyo). 2009 Jun;57(6):636-8. doi: 10.1248/cpb.57.636.
Wei Wang  1 ,  Xing-Cong Li ,  Zulfiqar Ali ,  Ikhlas Ahmed Khan
Affiliations
  • 1. National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, MS 38677, U.S.A.
PMID: 19483351 DOI: 10.1248/cpb.57.636
Abstract

Two new C(13) nor-isoprene glycosides, (6S,9S)-6,9-dihydroxymegastiman-4-en-9-O-beta-D-glucopyranoside (1) and (6S,9S)-6,9-dihydroxymegastiman-4-en-9-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (2) were isolated from the leaves of Casearia sylvestris, along with icariside B(5) (3), byzantionoside B (4), blumenol B (5), blumenol C (6) and loliolide (7). The structures of these compounds were determined on the basis of 1D and 2D NMR, MS and circular dichroism (CD) spectroscopic analyses, chemical methods and comparison with the literature data.

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