Two flavonoid dimers from Sarcandra hainanensis (PEI) SWAMY et BAILEY
- Chem Pharm Bull (Tokyo). 2009 Jul;57(7):743-6. doi: 10.1248/cpb.57.743.
Affiliations
- 1. Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College.
PMID: 19571424
DOI: 10.1248/cpb.57.743
Abstract
Two new flavonoid dimers (1, 2) consisting of flavan-chalcone together with three known compounds (3-5) were isolated from the ethanol extract of the whole Plants of Sarcandra hainanensis. Their structures were determined by extensive spectroscopic analysis. Human immunodeficiency virus-1 integrase inhibition activities of compounds 1 and 2 were evaluated and they showed weak activities with IC(50) at 18.05 and 25.27 muM, respectively.
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