A new triglucosylated naphthalene glycoside from Aloe vera L

  • Fitoterapia. 2010 Jan;81(1):59-62. doi: 10.1016/j.fitote.2009.07.006.
Qing-Yun Yang  1 ,  Chun-Suo Yao ,  Wei-Shuo Fang
Affiliations
  • 1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education and Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.
PMID: 19638305 DOI: 10.1016/j.fitote.2009.07.006
Abstract

A new triglucosylated naphthalene derivative, named aloveroside A (1), together with two known anthraquinone dimers and two 6-phenyl-2-pyrone derivatives, was isolated from the Aloe vera ethanolic extracts. The structure of 1 was established as 1-(((4-(1-O-beta-D-glucopyranosyl -(1-->4)-beta-D-xylopyranoside)-hydroxymethyl)-1-hydroxy-8-O-alpha-L-rhamnopyranoside)naphthalene-2-yl)-ethanone by means of spectroscopic evidences and chemical methods. All these compounds were tested for their BACE inhibitory activity but no significant activities were found.

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