Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody

  • Lab Chip. 2010 Jan 7;10(1):27-9. doi: 10.1039/b917959c.
Jason P Gleghorn  1 ,  Erica D Pratt ,  Denise Denning ,  He Liu ,  Neil H Bander ,  Scott T Tagawa ,  David M Nanus ,  Paraskevi A Giannakakou ,  Brian J Kirby
Affiliations
  • 1. Sibley School of Mechanical & Aerospace Engineering, College of Engineering, Cornell University, Ithaca, NY 14853, USA.
PMID: 20024046 DOI: 10.1039/b917959c
Abstract

Geometrically enhanced differential immunocapture (GEDI) and an antibody for prostate-specific membrane antigen (PSMA) are used for high-efficiency and high-purity capture of prostate circulating tumor cells from peripheral whole blood samples of castrate-resistant prostate Cancer patients.