Sesquiterpenes and dimeric sesquiterpenoids from Sarcandra glabra

  • J Nat Prod. 2010 Jan;73(1):45-50. doi: 10.1021/np9006469.
Xiu-Feng He  1 ,  Sheng Yin ,  Yin-Chun Ji ,  Zu-Shang Su ,  Mei-Yu Geng ,  Jian-Min Yue
Affiliations
  • 1. State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.
PMID: 20038159 DOI: 10.1021/np9006469
Abstract

Two new Sesquiterpenes, sarcandralactones A (1) and B (2), and five new dimeric sesquiterpenoids, sarcandrolides A-E (3-7), along with 10 known compounds were isolated from the whole Plants of Sarcandra glabra. Their structures were elucidated on the basis of spectroscopic analysis. Some of the new isolates exhibit significant cytotoxicities when tested against a small panel of tumor cell lines.