New cucurbitane-type triterpenoids from Bryonia aspera

  • Planta Med. 2010 Jul;76(10):1014-7. doi: 10.1055/s-0029-1240840.
Shamim Sahranavard  1 ,  Farzaneh Naghibi ,  Karsten Siems ,  Kristina Jenett-Siems
Affiliations
  • 1. Pharmacognosy Department, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. [email protected]
PMID: 20108178 DOI: 10.1055/s-0029-1240840
Abstract

Phytochemical investigation of the chloroform extract of BRYONIA ASPERA roots resulted in the isolation and structure elucidation of two new cucurbitacins (1, 2) together with eight known cucurbitane derivatives (6-13), the pentacyclic triterpene bryonolic acid (5) and two hydroxybenzoic acid amides (3, 4). Their structures were elucidated by spectroscopic analysis, including 2D NMR techniques.

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