Discovery of 1-(2,4-dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophen-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist

Ming-Shiu Hung  ¹ ,  Chun-Ping Chang ,  Ting-Chieh Li ,  Teng-Kuang Yeh ,  Jen-Shin Song ,  Yinchiu Lin ,  Chien-Huang Wu ,  Po-Chu Kuo ,  Prashanth K Amancha ,  Ying-Chieh Wong ,  Wen-Chi Hsiao ,  Yu-Sheng Chao ,  Kak-Shan Shia