Tirucallane-type alkaloids from the bark of Dysoxylum laxiracemosum
- J Nat Prod. 2010 Aug 27;73(8):1385-8. doi: 10.1021/np100307f.
Affiliations
- 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
PMID: 20669932
DOI: 10.1021/np100307f
Abstract
Eight novel tirucallane-type Alkaloids (1-8) and 11 known compounds were isolated from a methanol extract of the bark of Dysoxylum laxiracemosum. The structures of 1-8 were elucidated using extensive NMR spectrometric and mass spectroscopic methods. Compounds 1 and 5, named laxiracemosins A and E, showed significant cytotoxicity against five human Cancer cell lines.
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