Heterocyclic compounds and aromatic diglycosides from Bretschneidera sinensis

  • J Nat Prod. 2010 Sep 24;73(9):1582-5. doi: 10.1021/np1002934.
Chun-Mei Liu  1 Bo Li Yun-Heng Shen Wei-Dong Zhang
Affiliations
  • 1. Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, People's Republic of China.
Abstract

Two new heterocyclic compounds, bretschneiderazines A and B (1, 2), three new aromatic diglycosides, bretschneiderosides A-C (3-5), and three known aromatic diglycosides, 6-8, were isolated from Bretschneidera sinensis. The structure of bretschneiderazine A (1) was confirmed by single-crystal X-ray diffraction analysis. Bretschneiderazine A (1) showed moderate activity against the NCI-H446 cell line.