Synthesis and antifungal evaluation of 6-hydroxy-1H-carbazole-1,4(9H)-diones

  • Bioorg Med Chem Lett. 2011 Jan 1;21(1):427-30. doi: 10.1016/j.bmcl.2010.10.124.
Chung-Kyu Ryu  1 ,  Seung-Yon Lee ,  Na Young Kim ,  Jung An Hong ,  Joo Hee Yoon ,  Aram Kim
Affiliations
  • 1. College of Pharmacy, Ewha Womans University, Seodaemun-ku, Seoul 120-750, Republic of Korea. [email protected]
PMID: 21075635 DOI: 10.1016/j.bmcl.2010.10.124
Abstract

6-Hydroxy-1H-carbazole-1,4(9H)-diones were synthesized and tested for in vitro Antifungal activity against two pathogenic strains of fungi. Among them tested, many compounds showed good Antifungal activity. The results suggest that 6-hydroxy-1H-carbazole-1,4(9H)-diones would be potent Antifungal agents.

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